![]() ![]() But both viruses can cause either genital or oral herpes, and HSV 1 is now the leading cause of genital herpes in the UK. HSV 1 is most commonly associated with oral herpes, while HSV 2 is most commonly associated with genital herpes. Genital herpes involves painful, fluid-filled blisters in the genital or anal areas, sometimes accompanied by fever, headache, muscle ache and a general feeling of being unwell. These can occasionally develop on the nostrils, on the gums or on the roof of the mouth. Oral herpes causes tingling or painful fluid-filled blisters on the edge of the lip where it meets the skin of the face (‘cold sores’). There are also two places that herpes can affect: your mouth/lips (oral herpes) and your genital/anal area (genital herpes). There are two main types of herpes virus, HSV 1 and 2.
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